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Dr Patrick Howlett

Concentrations of respirable crystalline silica and radon among tanzanite mining communities in Mererani, Tanzania

Article

Background

Globally, the number of small-scale miners (SSM) is estimated to be more than 25 million, but it supports the livelihoods of around 100 million individuals. In Tanzania, the number of SSM has increased from an estimated 150,000 in 1987 to ~1.5 million in 2017. The miners are at a high risk of occupational-related health challenges. The study aimed to assess the concentrations of respirable crystalline silica (RCS) and radon among the tanzanite mining communities in Simanjiro District, Tanzania.

A call to invest in post-TB lung disease to halt TB transmission in communities

Article

Dear Editor We undertook an evaluation of former TB patients for pulmonary rehabilitation. Our diagnostic evaluation aimed to implement clinical standards for post-TB lung disease (PTLD) using operational research. 1 Nightingale et al. also issued a clinical statement, addressing diverse post-TB morbidities such as social, economic, neurological, cardiovascular, PTLD and psychiatric impairments. 2 In low-and middle-income African countries (such as Sudan, Ethiopia and Kenya), only 4 in 10 clinicians can diagnose PTLD, contributing to an underestimation of its burden.

Prevalence and determinants of evidence of silicosis and impaired lung function among small scale tanzanite miners and the peri-mining community in northern Tanzania

Article

Limited data among miners in Tanzania suggests prevalence of silicosis, obstructive lung disease and restrictive lung disease to be around 1.6%, 1.9% and 8.8% respectively. Our study aimed to determine the prevalence and factors associated with silicosis and impaired lung function among tanzanite mining community in northern Tanzania. We conducted a cross-sectional study, involving 330 miners and 330 peri-mining community members in Mererani mines.

Relationship between cumulative silica exposure and silicosis: a systematic review and dose-response meta-analysis

Article
Silicosis, a chronic respiratory disease caused by crystalline silica exposure, is a persistent global lung health issue. No systematic review of the relationship between cumulative respirable crystalline silica (RCS) exposure and silicosis exists. UK exposure limits are currently under review. We therefore performed a systematic review and dose-response meta-analysis of this relationship.

Confronting the growing epidemic of silicosis and tuberculosis among small-scale miners

Editorial

An estimated 49ยท5 million small-scale miners worldwide are exposed to high concentrations of silica during their work. The substantial morbidity and mortality of silicosis and tuberculosis among workers exposed to such intensities have been documented. This Viewpoint raises concern at the failure to respond to a growing epidemic of lung disease (predominantly silicosis and tuberculosis) among small-scale miners.

Dr Patrick Howlett

MRC Clinical Research Fellow (National Heart and Lung Institute)

Patrick is a Medical Research Council (MRC) PhD Clinical Research Fellow at the National Heart and Lung Institute, Imperial College London and is a Respiratory Registrar in Northwest London. His main research interest is occupational and infectious lung disease, particularly among small-scale and informal miners. His current PhD project is titled: Silicosis and Tuberculosis among small-scale miners in Northern Tanzania (SilicoTB). The project is a cross-sectional and cohort study investigating the burden and determinants of silicosis and tuberculosis among a group of Tanzanite gemstone miners. His previous work includes understanding the spirometry determinants of respiratory infection in children, and describing the clinical features of Ebola Virus Disease. 

Current research:

  • Silicosis and tuberculosis among small scale miners in northern Tanzania
  • Lung function determinants of respiratory infection in children

See a list of recent publications by Dr Patrick Howlett.

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